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Scientist/Senior Scientist, Material Sciences

Karuna Therapeutics

Karuna Therapeutics

Princeton, NJ, USA
Posted on Mar 13, 2025

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

The Protein, Bioanalysis, and Material Sciences (PMBS) group is part of the Precision Medicine, Bioanalytical and Translational Sciences (PMBATS) team. PMBATS leads internal and external bioanalytical and diagnostic research & development activities to support multiple disease areas of interest including hematological malignancies, inflammatory disease programs, neuroscience, cardiovascular, fibrosis, and solid tumor indications. The PMBATS group integrates scientific insights of multiple functions to provide innovative solutions that will make precision medicine a reality for the patients and health care providers we serve.

The primary purpose of this position is to design, execute, and analyze data for laboratory experiments which characterize protein reagents for use across multiple technology platforms, including but not limited to: Flow cytometry, IHC, and immunoassays. In this role the individual will be responsible for collaborating and communicating across the organization to assure on-time delivery of high-quality characterized materials.

Responsibilities:

  • Works with limited supervision to design, execute, and analyze laboratory experiments to assess the biophysical/binding properties and physicochemical properties of antibody and non-antibody protein reagents using BLI, SPR, HRMS, SEC-MALS, and other technologies.

  • Works with limited supervision to design and execute method development experiments for immunoassays.

  • Work with limited supervision to perform conjugations/purification of antibody and non-antibody proteins.

  • Works with limited supervision to interpret results, plan next steps, compile final data summaries, and present results to stakeholders.

  • Collaborate with internal stakeholders to understand project needs and relay information back to the group. .

  • Troubleshoots assay problems and instrument malfunctions.

  • Maintains required training per BMS standard operating procedures.

  • Maintains and completes notebooks and other documentation as per departmental guidelines.

  • Achieves objectives in a manner consistent with the BMS Behaviors

  • May contribute to writing and presentation of findings in the form of posters, publications, and oral presentations (internal and external)

Basic Qualifications:

For Scientist Level:

  • Bachelor’s Degree with 5+ years of related industry experience

  • Master’s Degree with 3+ years of related industry experience

  • Ph.D. in related field with 0 years of industry experience

For Senior Scientist Level:

Bachelor's Degree with 6+ years of related industry experience

Master's Degree with 5+ years of related industry experience

Ph.D. in related field with 2+ years of industry experience

Preferred Qualifications:

  • Experience with of BLI or SPR

  • Experience with HRMS, SEC, RP chromatography, and Protein concentration techniques.

  • Thorough knowledge of bioconjugation of antibody and non-antibody proteins.

  • Knowledge in the development and validation of regulated pharmacokinetic, immunogenicity, and biomarker immunoassays.

  • Familiarity with antibody and non-antibody protein generation.

  • Knowledge of the drug discovery and development process.

  • Familiarity with MALDI-MS for protein analysis.

  • Good verbal and written communication skills and the ability to independently interpret and deliver results.

  • Ability to effectively work across levels and functions with both internal and external stakeholders.

  • Excellent problem-solving skills.

#LI-ONSITE

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.